Identification of Transcription Factors for Lineage-Specific ESC Differentiation

A network of transcription factors (TFs) determines cell identity, but identity can be altered by overexpressing a combination of TFs. However, choosing and verifying combinations of TFs for specific cell differentiation have been daunting due to the large number of possible combinations of ∼2,000 T...

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Vydáno v:	Stem cell reports Ročník 1; číslo 6; s. 545 - 559
Hlavní autoři:	Yamamizu, Kohei, Piao, Yulan, Sharov, Alexei A., Zsiros, Veronika, Yu, Hong, Nakazawa, Kazu, Schlessinger, David, Ko, Minoru S.H.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Elsevier Inc 17.12.2013 Elsevier
Témata:	Animals Blood Cells - cytology Blood Cells - metabolism Cell Differentiation - genetics Cell Line Cell Lineage Embryonic Stem Cells - cytology Embryonic Stem Cells - metabolism Gene Expression Profiling Gene Expression Regulation Hepatocytes - cytology Hepatocytes - metabolism Mice Muscle Cells - cytology Muscle Cells - metabolism Neurons - cytology Neurons - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Transcription Factors - genetics Transcription Factors - metabolism Transcription Factors - physiology
ISSN:	2213-6711, 2213-6711
On-line přístup:	Získat plný text
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