The hepatitis delta virus: Replication and pathogenesis

Hepatitis delta virus (HDV) is a defective virus and a satellite of the hepatitis B virus (HBV). Its RNA genome is unique among animal viruses, but it shares common features with some plant viroids, including a replication mechanism that uses a host RNA polymerase. In infected cells, HDV genome repl...

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Bibliographic Details
Published in:	Journal of hepatology Vol. 64; no. 1; pp. S102 - S116
Main Authors:	Sureau, Camille, Negro, Francesco
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.04.2016
Subjects:	Chronic hepatitis Cirrhosis Gastroenterology and Hepatology Hepatitis D - metabolism Hepatitis D - pathology Hepatitis D - virology Hepatitis Delta Virus - physiology Hepatocellular carcinoma Hepatocytes - pathology Hepatocytes - virology Humans RNA, Viral - genetics Virion - genetics Viroids Virus Replication ORF S-HDAg HDAg HSPG AGL HCC Hepatocellular carcinoma ADAR SVP L-HDAg Cirrhosis RNP RdRp DIPA Chronic hepatitis NTCP Viroids HDV HBV NES delta-interacting protein A subviral particle hepatitis B virus open reading frame large-HDAg sodium taurocholate cotransporting polypeptide adenosine deaminase acting on RNA heparan sulfate proteoglycan hepatitis delta virus hepatocellular carcinoma ribonucleoprotein hepatitis delta antigen RNA-dependent RNA polymerase nuclear export signal small-HDAg antigenic loop
ISSN:	0168-8278, 1600-0641
Online Access:	Get full text
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