Complement gene variants in relation to autoantibodies to beta cell specific antigens and type 1 diabetes in the TEDDY Study

A total of 15 SNPs within complement genes and present on the ImmunoChip were analyzed in The Environmental Determinants of Diabetes in the Young (TEDDY) study. A total of 5474 subjects were followed from three months of age until islet autoimmunity (IA: n = 413) and the subsequent onset of type 1 d...

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Veröffentlicht in:	Scientific reports Jg. 6; H. 1; S. 27887
Hauptverfasser:	Törn, Carina, Liu, Xiang, Hagopian, William, Lernmark, Åke, Simell, Olli, Rewers, Marian, Ziegler, Anette-G, Schatz, Desmond, Akolkar, Beena, Onengut-Gumuscu, Suna, Chen, Wei-Min, Toppari, Jorma, Mykkänen, Juha, Ilonen, Jorma, Rich, Stephen S., She, Jin-Xiong, Sharma, Ashok, Steck, Andrea, Krischer, Jeffrey
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 16.06.2016 Nature Publishing Group
Schlagworte:	45 45/61 631/208/205 692/308/2056 Antigens Autoantibodies Autoimmune diseases Basic Medicine Child, Preschool Clinical Medicine Complement C3 - genetics Complement C3 - immunology Cytotoxicity Diabetes Diabetes Mellitus, Type 1 - genetics Diabetes Mellitus, Type 1 - immunology Endocrinology and Diabetes Endokrinologi och diabetes Enzymes Female Genes Haplotypes Health risk assessment Humanities and Social Sciences Humans Immune system Infant Infant, Newborn Insulin-Secreting Cells Klinisk medicin Lectins Male Medical and Health Sciences Medical Genetics and Genomics (including Gene Therapy) Medicin och hälsovetenskap Medicinsk genetik och genomik (Här ingår: Genterapi) Medicinska och farmaceutiska grundvetenskaper multidisciplinary Pathogens Pediatrics Polymorphism, Single Nucleotide Proteins Science Science (multidisciplinary) United States > US Finland
ISSN:	2045-2322, 2045-2322
Online-Zugang:	Volltext
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