Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS–) vs. Alternatively Activated Macrophages

Macrophages are found in tissues, body cavities, and mucosal surfaces. Most tissue macrophages are seeded in the early embryo before definitive hematopoiesis is established. Others are derived from blood monocytes. The macrophage lineage diversification and plasticity are key aspects of their functi...

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Bibliographic Details
Published in:Frontiers in immunology Vol. 10; p. 1084
Main Authors: Orecchioni, Marco, Ghosheh, Yanal, Pramod, Akula Bala, Ley, Klaus
Format: Journal Article
Language:English
Published: Switzerland Frontiers Media S.A 24.05.2019
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ISSN:1664-3224, 1664-3224
Online Access:Get full text
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