Fine-tuning the ubiquitin code at DNA double-strand breaks: deubiquitinating enzymes at work

Ubiquitination is a reversible protein modification broadly implicated in cellular functions. Signaling processes mediated by ubiquitin (ub) are crucial for the cellular response to DNA double-strand breaks (DSBs), one of the most dangerous types of DNA lesions. In particular, the DSB response criti...

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Veröffentlicht in:	Frontiers in genetics Jg. 6; S. 282
1. Verfasser:	Citterio, Elisabetta
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	Switzerland Frontiers Media S.A 08.09.2015
Schlagworte:	Chromatin Deubiquitinating enzymes DNA damage response (DDR) DNA Double-Strand Breaks (DSBs) DUBs Genetics Ubiquitin deubiquitinating enzymes (DUBs) DNA damage response (DDR) cancer chromatin hematopoietic stem cell (HSC) histone H2A ubiquitin DNA double-strand breaks (DSBs)
ISSN:	1664-8021, 1664-8021
Online-Zugang:	Volltext
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