Frequencies of region of difference 1 antigen-specific but not purified protein derivative-specific gamma interferon-secreting T cells correlate with the presence of tuberculosis disease but do not distinguish recent from remote latent infections

The majority of individuals infected with Mycobacterium tuberculosis achieve lifelong immune containment of the bacillus. What constitutes this effective host immune response is poorly understood. We compared the frequencies of gamma interferon (IFN-gamma)-secreting T cells specific for five region...

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Vydáno v:	Infection and immunity Ročník 77; číslo 12; s. 5486
Hlavní autoři:	Hinks, Timothy S C, Dosanjh, Davinder P S, Innes, John A, Pasvol, Geoffrey, Hackforth, Sarah, Varia, Hansa, Millington, Kerry A, Liu, Xiao-Qing, Bakir, Mustafa, Soysal, Ahmet, Davidson, Robert N, Gunatheesan, Rubamalar, Lalvani, Ajit
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.12.2009
Témata:	Adolescent Adult Antigens, Bacterial - immunology Bacterial Proteins - immunology Child Female Humans Immunoenzyme Techniques - methods Interferon-gamma - secretion Male Middle Aged Mycobacterium tuberculosis - immunology T-Lymphocytes - immunology Tuberculosis - diagnosis Tuberculosis - immunology Young Adult
ISSN:	1098-5522, 1098-5522
On-line přístup:	Zjistit podrobnosti o přístupu
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