PD-L1 Distribution and Perspective for Cancer Immunotherapy—Blockade, Knockdown, or Inhibition

Cancer immunotherapy involves blocking the interactions between the PD-1/PD-L1 immune checkpoints with antibodies. This has shown unprecedented positive outcomes in clinics. Particularly, the PD-L1 antibody therapy has shown the efficiency in blocking membrane PD-L1 and efficacy in treating some adv...

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Bibliographic Details

Published in:	Frontiers in immunology Vol. 10; p. 2022
Main Authors:	Wu, Yilun, Chen, Weiyu, Xu, Zhi Ping, Gu, Wenyi
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 27.08.2019
Subjects:	cancer immunotherapy cellular PD-L1 distribution gene silencing Immunology PD-1/PD-L1 immune checkpoint PD-L1 regulation signaling pathway inhibitor cancer immunotherapy gene silencing signaling pathway inhibitor PD-L1 regulation combination therapy PD-1/PD-L1 immune checkpoint cellular PD-L1 distribution
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
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