TREM1/3 Deficiency Impairs Tissue Repair After Acute Kidney Injury and Mitochondrial Metabolic Flexibility in Tubular Epithelial Cells

Long-term sequelae of acute kidney injury (AKI) are associated with incomplete recovery of renal function and the development of chronic kidney disease (CKD), which can be mediated by aberrant innate immune activation, mitochondrial pathology, and accumulation of senescent tubular epithelial cells (...

Full description

Bibliographic Details

Published in:	Frontiers in immunology Vol. 10; p. 1469
Main Authors:	Tammaro, Alessandra, Scantlebery, Angelique M. L., Rampanelli, Elena, Borrelli, Cristiana, Claessen, Nike, Butter, Loes M., Soriani, Alessandra, Colonna, Marco, Leemans, Jaklien C., Dessing, Mark C., Florquin, Sandrine
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 09.07.2019
Subjects:	epithelial innate immunity Immunology ischemia/reperfusion injury maladaptive repair mitochondrial metabolism renal repair tubular cell senescence tubular cell senescence maladaptive repair renal repair epithelial innate immunity ischemia/reperfusion injury mitochondrial metabolism
ISSN:	1664-3224, 1664-3224
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!