Impact of Cardiorespiratory Fitness on All-Cause and Disease-Specific Mortality: Advances Since 2009

Cardiorespiratory fitness (CRF) has been one of the most widely examined physiological variables, particularly as it relates to functional capacity and human performance. Over the past three decades, CRF has emerged as a strong, independent predictor of all-cause and disease-specific mortality. The...

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Published in:Progress in cardiovascular diseases Vol. 60; no. 1; pp. 11 - 20
Main Authors: Harber, Matthew P., Kaminsky, Leonard A., Arena, Ross, Blair, Steven N., Franklin, Barry A., Myers, Jonathan, Ross, Robert
Format: Journal Article
Language:English
Published: United States Elsevier Inc 01.07.2017
Subjects:
Aerobic capacity
Cardiovascular
Cardiovascular disease
Exercise
Physical activity
VO2max
O2
Physical activity
T2D
Cardiovascular disease
CPX
HFH
VA
CR
CVD
PA
PAD
CV
Exercise
CRF
UK
ACLS
VO2max
Aerobic capacity
AHA
NHANES
MI
MET
CHD
BMI
Myocardial infarction
Type 2 diabetes
Cardiovascular
Physical Activity
Veterans Affairs Medical Centers
Body mass index
Cardiopulmonary exercise testing
Cardiac rehabilitation
Henry Ford Hospital
O 2
Oxygen
Peripheral arterial disease
United Kingdom
Coronary heart disease
Metabolic equivalent
American Heart Association
maximal oxygen consumption aerobic capacity
Cardiorespiratory fitness
Aerobics Center Longitudinal Study
National Health and Nutrition Examination Survey
VO(2max)
ISSN:0033-0620, 1873-1740, 1532-8643, 1873-1740
Online Access:Get full text
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Summary:Cardiorespiratory fitness (CRF) has been one of the most widely examined physiological variables, particularly as it relates to functional capacity and human performance. Over the past three decades, CRF has emerged as a strong, independent predictor of all-cause and disease-specific mortality. The evidence supporting the prognostic use of CRF is so powerful that the American Heart Association recently advocated for the routine assessment of CRF as a clinical vital sign. Interestingly, the continuity of evidence of the inverse relationship between CRF and mortality over the past decade exists despite a wide variation of methods used to assess CRF in these studies, ranging from the gold-standard method of directly measured maximal oxygen uptake (VO2max) during cardiopulmonary exercise testing to estimation from exercise tests and non-exercise prediction equations. This review highlights new knowledge and the primary advances since 2009, with specific reference to the impact variations in CRF have on all-cause and disease-specific mortality.
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ISSN:0033-0620
1873-1740
1532-8643
1873-1740
DOI:10.1016/j.pcad.2017.03.001