Interplay between Ubiquitin, SUMO, and Poly(ADP-Ribose) in the Cellular Response to Genotoxic Stress

Cells employ a complex network of molecular pathways to cope with endogenous and exogenous genotoxic stress. This multilayered response ensures that genomic lesions are efficiently detected and faithfully repaired in order to safeguard genome integrity. The molecular choreography at sites of DNA dam...

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Bibliographic Details

Published in:	Frontiers in genetics Vol. 7; p. 63
Main Authors:	Pellegrino, Stefania, Altmeyer, Matthias
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 19.04.2016
Subjects:	Cancer DNA damage response Genetics genome stability PARP SUMO Ubiquitin genome stability DDR SUMO DNA damage response PARP cancer poly(ADP-ribose) ubiquitin
ISSN:	1664-8021, 1664-8021
Online Access:	Get full text
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