Cardiac safety of multidrug-resistant tuberculosis treatment: moving towards individualised monitoring

A heart rate-corrected QT interval (QTc) of 500 ms or more increases the risk of potentially fatal ventricular arrhythmias, including torsade de pointes.2 Despite the frequent, long-term use of QT interval-prolonging drugs, including moxifloxacin, which is used as a positive control in thorough QT s...

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Bibliographic Details
Published in:	The Lancet infectious diseases Vol. 21; no. 7; pp. 894 - 895
Main Authors:	Hewison, Catherine, Guglielmetti, Lorenzo
Format:	Journal Article
Language:	English
Published:	United States Elsevier Ltd 01.07.2021 Elsevier Limited New York, NY : Elsevier Science ; The Lancet Pub. Group, 2001
Subjects:	Albumins Antibiotics Bacteriology Cardiac arrhythmia Clinical trials Drug resistance Drugs EKG Heart rate HIV Human immunodeficiency virus Infectious diseases Life Sciences Microbiology and Parasitology Monitoring Moxifloxacin Multidrug resistance Prolongation Rifampin Risk factors Telemedicine Torsades de pointes Tuberculosis Ventricle
ISSN:	1473-3099, 1474-4457, 1474-4457
Online Access:	Get full text
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