Store‐operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease

Inflammatory bowel disease (IBD) is characterized by dysregulated intestinal immune responses. Using mass cytometry (CyTOF) to analyze the immune cell composition in the lamina propria (LP) of patients with ulcerative colitis (UC) and Crohn's disease (CD), we observed an enrichment of CD4 + eff...

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Veröffentlicht in:	EMBO molecular medicine Jg. 14; H. 9; S. e15687 - n/a
Hauptverfasser:	Letizia, Marilena, Wang, Yin‐Hu, Kaufmann, Ulrike, Gerbeth, Lorenz, Sand, Annegret, Brunkhorst, Max, Weidner, Patrick, Ziegler, Jörn Felix, Böttcher, Chotima, Schlickeiser, Stephan, Fernández, Camila, Yamashita, Megumi, Stauderman, Kenneth, Sun, Katherine, Kunkel, Désirée, Prakriya, Murali, Sanders, Ashley, Siegmund, Britta, Feske, Stefan, Weidinger, Carl
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 07.09.2022 John Wiley and Sons Inc Springer Nature
Schlagworte:	Crohn's disease EMBO12 EMBO19 mass cytometry store‐operated calcium entry (SOCE) T cell transfer models of colitis ulcerative colitis store‐operated calcium entry (SOCE) Crohn's disease ulcerative colitis mass cytometry T cell transfer models of colitis
ISSN:	1757-4676, 1757-4684, 1757-4684
Online-Zugang:	Volltext
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