Store‐operated calcium entry controls innate and adaptive immune cell function in inflammatory bowel disease

Inflammatory bowel disease (IBD) is characterized by dysregulated intestinal immune responses. Using mass cytometry (CyTOF) to analyze the immune cell composition in the lamina propria (LP) of patients with ulcerative colitis (UC) and Crohn's disease (CD), we observed an enrichment of CD4 + eff...

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Bibliographic Details

Published in:	EMBO molecular medicine Vol. 14; no. 9; pp. e15687 - n/a
Main Authors:	Letizia, Marilena, Wang, Yin‐Hu, Kaufmann, Ulrike, Gerbeth, Lorenz, Sand, Annegret, Brunkhorst, Max, Weidner, Patrick, Ziegler, Jörn Felix, Böttcher, Chotima, Schlickeiser, Stephan, Fernández, Camila, Yamashita, Megumi, Stauderman, Kenneth, Sun, Katherine, Kunkel, Désirée, Prakriya, Murali, Sanders, Ashley, Siegmund, Britta, Feske, Stefan, Weidinger, Carl
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 07.09.2022 John Wiley and Sons Inc Springer Nature
Subjects:	Crohn's disease EMBO12 EMBO19 mass cytometry store‐operated calcium entry (SOCE) T cell transfer models of colitis ulcerative colitis store‐operated calcium entry (SOCE) Crohn's disease ulcerative colitis mass cytometry T cell transfer models of colitis
ISSN:	1757-4676, 1757-4684, 1757-4684
Online Access:	Get full text
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