Skeletal Muscle mRNA Splicing Variants Association With Four Different Fitness and Energetic Measures in the GESTALT Study

ABSTRACT Background Physical activity is essential for maintaining muscle mitochondrial function and aerobic capacity. The molecular mechanisms underlying such protective effects are incompletely understood, in part because it is difficult to separate the effects of disease status and physical activ...

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Vydané v:	Journal of cachexia, sarcopenia and muscle Ročník 16; číslo 1; s. e13603 - n/a
Hlavní autori:	Donega, Stefano, Banskota, Nirad, Gupta, Esha, Gonzalez‐Freire, Marta, Moore, Ann Zenobia, Ubaida‐Mohien, Ceereena, Munk, Rachel, Zukley, Linda, Piao, Yulan, Bergeron, Chris, Bergeron, Jan, Bektas, Arsun, Zampino, Marta, Stagg, Carole, Indig, Fred, Hartnell, Lisa M., Kaileh, Mary, Fishbein, Kenneth, Spencer, Richard G., Gorospe, Myriam, De, Supriyo, Egan, Josephine M., Sen, Ranjan, Ferrucci, Luigi
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	Germany John Wiley & Sons, Inc 01.02.2025 John Wiley and Sons Inc Wiley
Predmet:	Adult Aged Aged, 80 and over Aging alternative splicing Bioenergetics Biopsy Body mass index Creatinine energy Energy Metabolism Exercise Exercise - physiology Female Fitness equipment Humans kPCr Male Maximum oxygen consumption Microscopy Middle Aged mitochondria respirometry Mitochondrial DNA muscle Muscle, Skeletal - metabolism Musculoskeletal system NMR Nuclear magnetic resonance Original physical activity Physical fitness Proteins Respiration RNA Splicing RNA, Messenger - metabolism Transcriptome VO2 Young Adult United States > US alternative splicing kPCr muscle VO2 exercise aging mitochondria respirometry energy physical activity
ISSN:	2190-5991, 2190-6009, 2190-6009
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