Translocator protein ligand, YL-IPA08, attenuates lipopolysaccharide-induced depression-like behavior by promoting neural regeneration

Translocator protein has received attention for its involvement in the pathogenesis of depression. This study assessed the effects of the new translocator protein ligand, YL-IPA08, on alleviating inflammation-induced depression-like behavior in mice and investigated its mechanism of action. Mice wer...

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Bibliographic Details
Published in:	Neural regeneration research Vol. 13; no. 11; pp. 1937 - 1944
Main Authors:	Zhang, Xiao-Ying, Zhang, Li-Ming, Mi, Wei-Dong, Li, Yun-Feng
Format:	Journal Article
Language:	English
Published:	India Medknow Publications and Media Pvt. Ltd 01.11.2018 Medknow Publications & Media Pvt. Ltd Anesthesia and Operation Center, Chinese PLA General Hospital, Beijing, China State Key Laboratory of Toxicology and Medical Countermeasures, Beijing, China%Anesthesia and Operation Center, Chinese PLA General Hospital, Beijing, China%State Key Laboratory of Toxicology and Medical Countermeasures, Beijing, China Medknow Publications & Media Pvt Ltd
Subjects:	Analysis Behavior Brain Depression, Mental Inflammation Laboratory animals Ligands Ligands (Biochemistry) Lipopolysaccharides Medical research Mental depression Mice Nervous system Neurogenesis Regeneration Beijing China United States > US China dentate gyrus neural regeneration translocator protein hippocampus neuroinflammation nerve regeneration depression lipopolysaccharide YL-IPA08
ISSN:	1673-5374, 1876-7958
Online Access:	Get full text
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