Novel Association of HK1 with Glycated Hemoglobin in a Non-Diabetic Population: A Genome-Wide Evaluation of 14,618 Participants in the Women's Genome Health Study

Type 2 diabetes is a leading cause of morbidity and mortality. While genetic variants have been found to influence the risk of type 2 diabetes mellitus, relatively few studies have focused on genes associated with glycated hemoglobin, an index of the mean blood glucose concentration of the preceding...

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Bibliographic Details
Published in:	PLoS genetics Vol. 4; no. 12; p. e1000312
Main Authors:	Paré, Guillaume, Chasman, Daniel I., Parker, Alexander N., Nathan, David M., Miletich, Joseph P., Zee, Robert Y., Ridker, Paul M.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.12.2008 Public Library of Science (PLoS)
Subjects:	Cohort Studies Continental Population Groups - genetics Diabetes Diabetes and Endocrinology/Type 2 Diabetes Diabetes Mellitus, Type 2 - epidemiology Diabetes Mellitus, Type 2 - genetics Diabetes Mellitus, Type 2 - metabolism Female Genetics and Genomics/Complex Traits Genome, Human Genome-Wide Association Study Glucose Glycated Hemoglobin A - genetics Glycated Hemoglobin A - metabolism Hemoglobin Hexokinase - genetics Hexokinase - metabolism Humans Middle Aged Physiology/Endocrinology Polymorphism, Single Nucleotide Risk Factors United States - epidemiology Womens health
ISSN:	1553-7404, 1553-7390, 1553-7404
Online Access:	Get full text
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