Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters

The pathogenesis of multiple sclerosis (MS), an autoimmune disease affecting the brain and spinal cord, remains poorly understood. Patients with MS typically present with recurrent episodes of neurological dysfunctions such as blindness, paresis, and sensory disturbances. Studies on experimental aut...

Full description

Saved in:

Bibliographic Details
Published in:	PloS one Vol. 10; no. 9; p. e0137429
Main Authors:	Miyake, Sachiko, Kim, Sangwan, Suda, Wataru, Oshima, Kenshiro, Nakamura, Masakazu, Matsuoka, Takako, Chihara, Norio, Tomita, Atsuko, Sato, Wakiro, Kim, Seok-Won, Morita, Hidetoshi, Hattori, Masahira, Yamamura, Takashi
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 14.09.2015 Public Library of Science (PLoS)
Subjects:	Adult Allergies Animal models Autoimmune diseases Bacteria Bacteroidetes - genetics Bacteroidetes - metabolism Bioinformatics Biology Blindness Brain Cell culture Clostridia Clostridium - classification Clostridium - genetics Clostridium - metabolism Clusters Dysbacteriosis Dysbiosis - metabolism Dysbiosis - microbiology Experimental allergic encephalomyelitis Female Gastrointestinal Microbiome High-Throughput Nucleotide Sequencing Humans Immunology Immunoregulation Inflammatory bowel disease Intestinal microflora Japan Lymphocytes Lymphocytes T Male Metabolites Microbiota Multiple sclerosis Multiple Sclerosis - microbiology Multiple Sclerosis - physiopathology Neurological diseases Neurosciences Paresis Pathogenesis Patients Phylogenetics Phylogeny Relative abundance Ribonucleic acid RNA RNA, Bacterial - genetics RNA, Ribosomal, 16S - genetics rRNA 16S Sequence Analysis, RNA Species Spinal cord Womens health Japan
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!