Effects of αTAT1 and HDAC5 on axonal regeneration in adult neurons

The role of posttranslational modifications in axonal injury and regeneration has been widely studied but there has been little consensus over the mechanism by which each modification affects adult axonal growth. Acetylation is known to play an important role in a variety of neuronal functions and i...

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Bibliographic Details
Published in:	PloS one Vol. 12; no. 5; p. e0177496
Main Authors:	Lin, Shen, Sterling, Noelle A., Junker, Ian P., Helm, Courtney T., Smith, George M.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 15.05.2017 Public Library of Science (PLoS)
Subjects:	Acetylation Acetyltransferases - genetics Acetyltransferases - metabolism Animals Axons Axons - physiology Biology and Life Sciences Cell cycle Cell division Cells, Cultured Chromatin Crushing Cytoplasm Enzymes Gene Expression HEK293 Cells Histone Deacetylases - genetics Histone Deacetylases - metabolism Homeostasis Hospitals Humans In vitro methods and tests Infections Kinases Laboratory animals Medical research Medicine Medicine and Health Sciences Microtubules Nerve Regeneration Nerves Neurons Neurons - physiology Neurosciences Outerwear Pediatrics Physical Sciences Plasmids Rats Regeneration Rehabilitation Sciatic nerve Studies Tubulin United States > US Pennsylvania
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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