Reduction of Acquisition time using Partition of the sIgnal Decay in Spectroscopic Imaging technique (RAPID-SI)

To overcome long acquisition times of Chemical Shift Imaging (CSI), a new Magnetic Resonance Spectroscopic Imaging (MRSI) technique called Reduction of Acquisition time by Partition of the sIgnal Decay in Spectroscopic Imaging (RAPID-SI) using blipped phase encoding gradients inserted during signal...

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Bibliographic Details
Published in:PloS one Vol. 13; no. 11; p. e0207015
Main Authors: Bhaduri, Sourav, Clement, Patricia, Achten, Eric, Serrai, Hacene
Format: Journal Article
Language:English
Published: United States Public Library of Science 07.11.2018
Public Library of Science (PLoS)
Subjects:
Acceleration
Algorithms
Biology and Life Sciences
Brain
Chemical equilibrium
Coding
Computer and Information Sciences
Data acquisition
Data collection
Data processing
Decay
Image reconstruction
In vivo methods and tests
Magnetic resonance
Magnetic resonance imaging
Magnetic resonance spectroscopy
Medicine and Health Sciences
Metabolites
Methods
Noise
Nuclear medicine
Organic chemistry
Partitions
Reduction
Research and Analysis Methods
Resonance
Spatial data
Spectroscopy
Spectrum analysis
ISSN:1932-6203, 1932-6203
Online Access:Get full text
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Summary:To overcome long acquisition times of Chemical Shift Imaging (CSI), a new Magnetic Resonance Spectroscopic Imaging (MRSI) technique called Reduction of Acquisition time by Partition of the sIgnal Decay in Spectroscopic Imaging (RAPID-SI) using blipped phase encoding gradients inserted during signal acquisition was developed. To validate the results using RAPID-SI and to demonstrate its usefulness in terms of acquisition time and data quantification; simulations, phantom and in vivo studies were conducted, and the results were compared to standard CSI. The method was based upon the partition of a magnetic resonance spectroscopy (MRS) signal into sequential sub-signals encoded using blipped phase encoding gradients inserted during signal acquisition at a constant time interval. The RAPID-SI technique was implemented on a clinical 3 T Siemens scanner to demonstrate its clinical utility. Acceleration of data collection was performed by inserting R (R = acceleration factor) blipped gradients along a given spatial direction during data acquisition. Compared to CSI, RAPID-SI reduced acquisition time by the acceleration factor R. For example, a 2D 16x16 data set acquired in about 17 min with CSI, was reduced to approximately 2 min with the RAPID-SI (R = 8). While the SNR of the acquired RAPID-SI signal was lower compared to CSI by approximately the factor √R, it can be improved after data pre-processing and reconstruction. Compared to CSI, RAPID-SI reduces acquisition time, while preserving metabolites information. Furthermore, the method is flexible and could be combined with other acceleration methods such as Parallel Imaging.
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Competing Interests: Authors Sourav Bhaduri, Eric Achten, and Hacene Serrai are named as inventors on a patent application "NMR spectroscopic chemical-shift imaging" (International patent application No. WO2018050306AI), which is related to the development of the pulse sequence. However, these interests have not influenced the interpretation of the data herein, and do not alter the authors' adherence to PLOS ONE policies on sharing data and materials.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0207015