Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study

Increased serum levels of C-reactive protein (CRP), an important component of the innate immune response, are associated with increased risk of cardiovascular disease (CVD). Multiple single nucleotide polymorphisms (SNP) have been identified which are associated with CRP levels, and Mendelian random...

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Bibliographic Details
Published in:	PloS one Vol. 14; no. 10; p. e0223574
Main Authors:	Best, Lyle G., Balakrishnan, Poojitha, Cole, Shelley A., Haack, Karin, Kocarnik, Jonathan M., Pankratz, Nathan, Anderson, Matthew Z., Franceschini, Nora, Howard, Barbara V., Lee, Elisa T., North, Kari E., Umans, Jason G., Yracheta, Joseph M., Navas-Acien, Ana, Voruganti, V. Saroja
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 17.10.2019 Public Library of Science (PLoS)
Subjects:	African Americans Alleles Biology and Life Sciences Biomarkers - blood Biomedical research C-reactive protein C-Reactive Protein - genetics Cancer Cardiovascular diseases Chromosomes Colon Colon cancer Colorectal cancer Diabetes Environmental health Family studies Female Gene loci Genetic analysis Genetic diversity Genetic Linkage Genetic markers Genetic Predisposition to Disease Genetic variance Genetic Variation Genetics, Population Genome-Wide Association Study Genomes Genomics Genotype Genotypes Health risks Health sciences Heart diseases Heritability Humans Immune response Indians, North American - genetics Influence Innate immunity Male Markers Medical research Medicine and Health Sciences Metabolism Microsatellites Minority & ethnic groups Native Americans Nucleotides Nutrition research Obesity Polymorphism, Single Nucleotide Population genetics Populations Proteins Public health Serum levels Single-nucleotide polymorphism Studies New York Ohio United States > US Texas Missouri
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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