XRCC1 gene variants and possible links with chromosome aberrations and micronucleus in active and passive smokers

► The present investigation was conducted to analyze the genotoxic effects of tobacco on active and passive smokers. ► Three types of genetic test methods were employed including chromosome, micronucleus and XRCC1 arg399gln polymorphism. ► A high level of chromosomal aberrations and micronucleus wer...

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Bibliographic Details
Published in:	Environmental toxicology and pharmacology Vol. 32; no. 2; pp. 185 - 192
Main Authors:	Chandirasekar, R., Suresh, K., Jayakumar, R., Venkatesan, R., Lakshman Kumar, B., Sasikala, K.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.09.2011
Subjects:	Cancer Case-Control Studies Cells, Cultured Chromosomal aberrations chromosome aberrations Chromosome Aberrations - chemically induced chromosomes Cytogenetics Cytogenetics - methods death DNA Damage DNA-Binding Proteins - genetics Emergency Epithelial Cells - physiology exposure duration Female genes genotoxicity Genotype Humans Lymphocytes - cytology Lymphocytes - physiology Male Micronuclei, Chromosome-Defective - chemically induced Mouth Mucosa - cytology myocardial infarction neoplasms Occupational Exposure Polymorphism Polymorphism, Single Nucleotide risk single nucleotide polymorphism smoking (habit) Smoking - adverse effects tobacco Tobacco addictive Tobacco Smoke Pollution - adverse effects toxins X-ray Repair Cross Complementing Protein 1 MN AS BMN PS CAs BLMN Chromosomal aberrations Tobacco addictive Cytogenetics Cancer Polymorphism Blood lymphocyte micronuclei Active smokers Micronuclei Passive smokers Buccal micronuclei
ISSN:	1382-6689, 1872-7077, 1872-7077
Online Access:	Get full text
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