Natural Killer Cells Are Characterized by the Concomitantly Increased Interferon-γ and Cytotoxicity in Acute Resolved Hepatitis B Patients

Natural killer (NK) cells are abundant in the liver and have been implicated in inducing hepatocellular damage in patients with chronic hepatitis B virus (HBV) infection. However, the role of NK cells in acute HBV infection remains to be elucidated. We comprehensively characterized NK cells and inve...

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Bibliographic Details
Published in:	PloS one Vol. 7; no. 11; p. e49135
Main Authors:	Zhao, Juanjuan, Li, Yonggang, Jin, Lei, Zhang, Shuye, Fan, Rong, Sun, Yanling, Zhou, Chunbao, Shang, Qinghua, Li, Wengang, Zhang, Zheng, Wang, Fu-Sheng
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.11.2012 Public Library of Science (PLoS)
Subjects:	Acute Disease Adolescent Adult Aged Alanine Alanine transaminase Biophysics CD56 Antigen - biosynthesis Cell activation Chronic infection Cytokines Cytolytic activity Cytotoxicity Deoxyribonucleic acid DNA DNA, Viral - genetics Female Flow Cytometry Gastroenterology Hepatitis Hepatitis B Hepatitis B - blood Hepatitis B - therapy Hepatitis B virus Hepatitis B, Chronic - blood Hepatitis B, Chronic - therapy Hepatology Humans Immunohistochemistry - methods Immunotherapy Infections Inflammation Interferon Interferon-gamma - metabolism Killer Cells, Natural - cytology Liver Liver - pathology Lymphocytes Male Medicine Middle Aged Natural killer cells Pathogenesis Patients Receptors T cell receptors Toxicity Viruses Beijing China China
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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