Valuation of Normal Range of Ankle Systolic Blood Pressure in Subjects with Normal Arm Systolic Blood Pressure

This study aimed to establish a normal range for ankle systolic blood pressure (SBP). A total of 948 subjects who had normal brachial SBP (90-139 mmHg) at investigation were enrolled. Supine BP of four limbs was simultaneously measured using four automatic BP measurement devices. The ankle-arm diffe...

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Bibliographic Details
Published in:PloS one Vol. 10; no. 6; p. e0122248
Main Authors: Gong, Yi, Cao, Kai-wu, Xu, Jin-song, Li, Ju-xiang, Hong, Kui, Cheng, Xiao-shu, Su, Hai
Format: Journal Article
Language:English
Published: United States Public Library of Science 08.06.2015
Public Library of Science (PLoS)
Subjects:
Adolescent
Adult
Age Distribution
Age groups
Aged
Ankle
Ankle - physiology
Arm - physiology
Atherosclerosis
Blood
Blood pressure
Blood Pressure - physiology
Cardiology
Extremities
Female
Geriatrics
Heart attacks
Heart failure
Humans
Hypertension
Male
Measuring instruments
Methods
Middle age
Middle Aged
Morbidity
Mortality
Older people
Reference Values
Statistical analysis
Systole - physiology
Young Adult
China
ISSN:1932-6203, 1932-6203
Online Access:Get full text
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Summary:This study aimed to establish a normal range for ankle systolic blood pressure (SBP). A total of 948 subjects who had normal brachial SBP (90-139 mmHg) at investigation were enrolled. Supine BP of four limbs was simultaneously measured using four automatic BP measurement devices. The ankle-arm difference (An-a) on SBP of both sides was calculated. Two methods were used for establishing normal range of ankle SBP: the 99% method was decided on the 99% reference range of actual ankle BP, and the An-a method was the sum of An-a and the low or up limits of normal arm SBP (90-139 mmHg). Whether in the right or left side, the ankle SBP was significantly higher than the arm SBP (right: 137.1 ± 16.9 vs 119.7 ± 11.4 mmHg, P<0.05). Based on the 99% method, the normal range of ankle SBP was 94~181 mmHg for the total population, 84~166 mmHg for the young (18-44 y), 107~176 mmHg for the middle-aged(45-59 y) and 113~179 mmHg for the elderly (≥ 60 y) group. As the An-a on SBP was 13 mmHg in the young group and 20 mmHg in both middle-aged and elderly groups, the normal range of ankle SBP on the An-a method was 103-153 mmHg for young and 110-160 mmHg for middle-elderly subjects. A primary reference for normal ankle SBP was suggested as 100-165 mmHg in the young and 110-170 mmHg in the middle-elderly subjects.
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These authors are co-first authors.
Conceived and designed the experiments: HS KH. Performed the experiments: YG KWC JSX JXL. Analyzed the data: KWC JXL. Contributed reagents/materials/analysis tools: HS XSC KH. Wrote the paper: HS XSC.
Competing Interests: The authors have declared that no competing interests exist.
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0122248