On the Mechanisms of Biliary Flux

Since the late 1950s, transport of bile in the liver has been described by the “osmotic concept,” according to which bile flows into the canaliculi toward the ducts, countercurrent to the blood flow in the sinusoids. However, because of the small size of canaliculi, it was so far impossible to obser...

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Bibliographic Details
Published in:	Hepatology (Baltimore, Md.) Vol. 74; no. 6; pp. 3497 - 3512
Main Authors:	Vartak, Nachiket, Drasdo, Dirk, Geisler, Fabian, Itoh, Tohru, P.J.Oude Elferink, Ronald, Graaf, Stan F.J., Chiang, John, Keitel, Verena, Trauner, Michael, Jansen, Peter, Hengstler, Jan G.
Format:	Journal Article
Language:	English
Published:	United States Wolters Kluwer Health, Inc 01.12.2021 Wiley-Blackwell
Subjects:	Animals Bile Bile - metabolism Bile Acids and Salts - metabolism Bile ducts Bile Ducts - metabolism Blood flow Cholestasis Computer Science Diffusion Fatty liver Hepatology Humans Liver - metabolism Liver diseases Mice Modeling and Simulation Osmosis
ISSN:	0270-9139, 1527-3350, 1527-3350
Online Access:	Get full text
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