Tumor-immune partitioning and clustering algorithm for identifying tumor-immune cell spatial interaction signatures within the tumor microenvironment

Growing evidence supports the importance of characterizing the organizational patterns of various cellular constituents in the tumor microenvironment in precision oncology. Most existing data on immune cell infiltrates in tumors, which are based on immune cell counts or nearest neighbor-type analyse...

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Veröffentlicht in:PLoS computational biology Jg. 21; H. 2; S. e1012707
Hauptverfasser: Lau, Mai Chan, Borowsky, Jennifer, Väyrynen, Juha P., Haruki, Koichiro, Zhao, Melissa, Dias Costa, Andressa, Gu, Simeng, da Silva, Annacarolina, Ugai, Tomotaka, Arima, Kota, Nguyen, Minh N., Takashima, Yasutoshi, Yeong, Joe, Tai, David, Hamada, Tsuyoshi, Lennerz, Jochen K., Fuchs, Charles S., Wu, Catherine J., Meyerhardt, Jeffrey A., Ogino, Shuji, Nowak, Jonathan A.
Format: Journal Article
Sprache:Englisch
Veröffentlicht: United States Public Library of Science 18.02.2025
Public Library of Science (PLoS)
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ISSN:1553-7358, 1553-734X, 1553-7358
Online-Zugang:Volltext
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