Analyzing complex traits with congenic strains

Congenic strains continue to be a fundamental resource for dissecting the genetic basis of complex traits. Traditionally, genetic variants (QTLs) that account for phenotypic variation in a panel of congenic strains are sought first by comparing phenotypes for each strain to the host (reference) stra...

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Vydané v:	Mammalian genome Ročník 21; číslo 5-6; s. 276 - 286
Hlavní autori:	Shao, Haifeng, Sinasac, David S, Burrage, Lindsay C, Hodges, Craig A, Supelak, Pamela J, Palmert, Mark R, Moreno, Carol, Cowley, Allen W. Jr, Jacob, Howard J, Nadeau, Joseph H
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	New York New York : Springer-Verlag 01.06.2010 Springer-Verlag Springer Nature B.V
Predmet:	Animal Genetics and Genomics Animals Animals, Congenic Biomedical and Life Sciences Cell Biology Chromosome Mapping chromosomes genetic variation genome Genotype Human Genetics Life Sciences linear models Mice Mice, Congenic Mice, Inbred C57BL Phenotype phenotypic variation Quantitative Trait Loci Rats Interval Mapping Minimum Span Tree Mean Arterial Pressure Sequential Method Host Strain
ISSN:	0938-8990, 1432-1777, 1432-1777
On-line prístup:	Získať plný text
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