Integrative analysis of drug response and clinical outcome in acute myeloid leukemia

Acute myeloid leukemia (AML) is a cancer of myeloid-lineage cells with limited therapeutic options. We previously combined ex vivo drug sensitivity with genomic, transcriptomic, and clinical annotations for a large cohort of AML patients, which facilitated discovery of functional genomic correlates....

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Vydané v:	Cancer cell Ročník 40; číslo 8; s. 850
Hlavní autori:	Bottomly, Daniel, Long, Nicola, Schultz, Anna Reister, Kurtz, Stephen E, Tognon, Cristina E, Johnson, Kara, Abel, Melissa, Agarwal, Anupriya, Avaylon, Sammantha, Benton, Erik, Blucher, Aurora, Borate, Uma, Braun, Theodore P, Brown, Jordana, Bryant, Jade, Burke, Russell, Carlos, Amy, Chang, Bill H, Cho, Hyun Jun, Christy, Stephen, Coblentz, Cody, Cohen, Aaron M, d'Almeida, Amanda, Cook, Rachel, Danilov, Alexey, Dao, Kim-Hien T, Degnin, Michie, Dibb, James, Eide, Christopher A, English, Isabel, Hagler, Stuart, Harrelson, Heath, Henson, Rachel, Ho, Hibery, Joshi, Sunil K, Junio, Brian, Kaempf, Andy, Kosaka, Yoko, Laderas, Ted, Lawhead, Matt, Lee, Hyunjung, Leonard, Jessica T, Lin, Chenwei, Lind, Evan F, Liu, Selina Qiuying, Lo, Pierrette, Loriaux, Marc M, Luty, Samuel, Maxson, Julia E, Macey, Tara, Martinez, Jacqueline, Minnier, Jessica, Monteblanco, Andrea, Mori, Motomi, Morrow, Quinlan, Nelson, Dylan, Ramsdill, Justin, Rofelty, Angela, Rogers, Alexandra, Romine, Kyle A, Ryabinin, Peter, Saultz, Jennifer N, Sampson, David A, Savage, Samantha L, Schuff, Robert, Searles, Robert, Smith, Rebecca L, Spurgeon, Stephen E, Sweeney, Tyler, Swords, Ronan T, Thapa, Aashis, Thiel-Klare, Karina, Traer, Elie, Wagner, Jake, Wilmot, Beth, Wolf, Joelle, Wu, Guanming, Yates, Amy, Zhang, Haijiao, Cogle, Christopher R, Collins, Robert H, Deininger, Michael W, Hourigan, Christopher S, Jordan, Craig T, Lin, Tara L, Martinez, Micaela E, Pallapati, Rachel R, Pollyea, Daniel A, Pomicter, Anthony D, Watts, Justin M, Weir, Scott J, Druker, Brian J, McWeeney, Shannon K, Tyner, Jeffrey W
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 08.08.2022
Predmet:	Cell Differentiation Cohort Studies Humans Leukemia, Myeloid, Acute - drug therapy Leukemia, Myeloid, Acute - genetics Receptors, Cell Surface - genetics Transcriptome targeted therapy JEDI leukemia stem cell eigengene LSC17 monocyte MEGF12 hematologic malignancy cell state
ISSN:	1878-3686, 1878-3686
On-line prístup:	Zistit podrobnosti o prístupe
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