Integrative analysis of drug response and clinical outcome in acute myeloid leukemia

Acute myeloid leukemia (AML) is a cancer of myeloid-lineage cells with limited therapeutic options. We previously combined ex vivo drug sensitivity with genomic, transcriptomic, and clinical annotations for a large cohort of AML patients, which facilitated discovery of functional genomic correlates....

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Bibliographic Details
Published in:	Cancer cell Vol. 40; no. 8; p. 850
Main Authors:	Bottomly, Daniel, Long, Nicola, Schultz, Anna Reister, Kurtz, Stephen E, Tognon, Cristina E, Johnson, Kara, Abel, Melissa, Agarwal, Anupriya, Avaylon, Sammantha, Benton, Erik, Blucher, Aurora, Borate, Uma, Braun, Theodore P, Brown, Jordana, Bryant, Jade, Burke, Russell, Carlos, Amy, Chang, Bill H, Cho, Hyun Jun, Christy, Stephen, Coblentz, Cody, Cohen, Aaron M, d'Almeida, Amanda, Cook, Rachel, Danilov, Alexey, Dao, Kim-Hien T, Degnin, Michie, Dibb, James, Eide, Christopher A, English, Isabel, Hagler, Stuart, Harrelson, Heath, Henson, Rachel, Ho, Hibery, Joshi, Sunil K, Junio, Brian, Kaempf, Andy, Kosaka, Yoko, Laderas, Ted, Lawhead, Matt, Lee, Hyunjung, Leonard, Jessica T, Lin, Chenwei, Lind, Evan F, Liu, Selina Qiuying, Lo, Pierrette, Loriaux, Marc M, Luty, Samuel, Maxson, Julia E, Macey, Tara, Martinez, Jacqueline, Minnier, Jessica, Monteblanco, Andrea, Mori, Motomi, Morrow, Quinlan, Nelson, Dylan, Ramsdill, Justin, Rofelty, Angela, Rogers, Alexandra, Romine, Kyle A, Ryabinin, Peter, Saultz, Jennifer N, Sampson, David A, Savage, Samantha L, Schuff, Robert, Searles, Robert, Smith, Rebecca L, Spurgeon, Stephen E, Sweeney, Tyler, Swords, Ronan T, Thapa, Aashis, Thiel-Klare, Karina, Traer, Elie, Wagner, Jake, Wilmot, Beth, Wolf, Joelle, Wu, Guanming, Yates, Amy, Zhang, Haijiao, Cogle, Christopher R, Collins, Robert H, Deininger, Michael W, Hourigan, Christopher S, Jordan, Craig T, Lin, Tara L, Martinez, Micaela E, Pallapati, Rachel R, Pollyea, Daniel A, Pomicter, Anthony D, Watts, Justin M, Weir, Scott J, Druker, Brian J, McWeeney, Shannon K, Tyner, Jeffrey W
Format:	Journal Article
Language:	English
Published:	United States 08.08.2022
Subjects:	Cell Differentiation Cohort Studies Humans Leukemia, Myeloid, Acute - drug therapy Leukemia, Myeloid, Acute - genetics Receptors, Cell Surface - genetics Transcriptome targeted therapy JEDI leukemia stem cell eigengene LSC17 monocyte MEGF12 hematologic malignancy cell state
ISSN:	1878-3686, 1878-3686
Online Access:	Get more information
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