The Role of Astrocytes in CNS Inflammation

Astrocytes are the most abundant cell type in the central nervous system (CNS), performing complex functions in health and disease. It is now clear that multiple astrocyte subsets or activation states (plastic phenotypes driven by intrinsic and extrinsic cues) can be identified, associated to specif...

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Bibliographic Details
Published in:	Trends in immunology Vol. 41; no. 9; pp. 805 - 819
Main Authors:	Giovannoni, Federico, Quintana, Francisco J.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.09.2020 Elsevier Limited
Subjects:	astrocyte subsets Astrocytes Astrocytes - cytology Astrocytes - immunology Central nervous system Central Nervous System - cytology Central Nervous System - immunology Disease Gene expression Genotype & phenotype Humans Inflammation Inflammation - immunology Kinases Morphology Nervous System Diseases - immunology Neurological diseases Phenotypes Phenotypic plasticity Proteins reactive astrocytes Tumor necrosis factor-TNF Viruses West Nile virus inflammation astrocyte subsets reactive astrocytes
ISSN:	1471-4906, 1471-4981, 1471-4981
Online Access:	Get full text
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