Mating activates the heme peroxidase HPX15 in the sperm storage organ to ensure fertility in Anopheles gambiae

Anopheles gambiae mosquitoes are major African vectors of malaria, a disease that kills more than 600,000 people every year. Given the spread of insecticide resistance in natural mosquito populations, alternative vector control strategies aimed at reducing the reproductive success of mosquitoes are...

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Vydáno v:	Proceedings of the National Academy of Sciences - PNAS Ročník 111; číslo 16; s. 5854
Hlavní autoři:	Shaw, W Robert, Teodori, Eleonora, Mitchell, Sara N, Baldini, Francesco, Gabrieli, Paolo, Rogers, David W, Catteruccia, Flaminia
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 22.04.2014
Témata:	Animal Structures - cytology Animal Structures - drug effects Animal Structures - enzymology Animal Structures - ultrastructure Animals Anopheles - drug effects Anopheles - enzymology Anopheles - genetics Ecdysone - pharmacology Enzyme Activation - drug effects Female Fertility - drug effects Fertility - genetics Gene Expression Regulation - drug effects Heme - metabolism Insect Proteins - genetics Insect Proteins - metabolism Male Peroxidase - genetics Peroxidase - metabolism Reverse Transcriptase Polymerase Chain Reaction Sexual Behavior, Animal - drug effects Spermatozoa - cytology Spermatozoa - drug effects Spermatozoa - enzymology Spermatozoa - ultrastructure Transcription, Genetic - drug effects
ISSN:	1091-6490, 1091-6490
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