Urinary Sodium and Potassium Excretion, Mortality, and Cardiovascular Events

In a large study in 17 countries, an estimated sodium intake that was either higher or lower than the average estimated sodium intake was associated with an increased risk of cardiovascular events. A higher-than-average potassium intake was associated with reduced risk. Most of the global population...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:The New England journal of medicine Jg. 371; H. 7; S. 612 - 623
Hauptverfasser: O'Donnell, Martin, Mente, Andrew, Rangarajan, Sumathy, McQueen, Matthew J, Wang, Xingyu, Liu, Lisheng, Yan, Hou, Lee, Shun Fu, Mony, Prem, Devanath, Anitha, Rosengren, Annika, Lopez-Jaramillo, Patricio, Diaz, Rafael, Avezum, Alvaro, Lanas, Fernando, Yusoff, Khalid, Iqbal, Romaina, Ilow, Rafal, Mohammadifard, Noushin, Gulec, Sadi, Yusufali, Afzal Hussein, Kruger, Lanthe, Yusuf, Rita, Chifamba, Jephat, Kabali, Conrad, Dagenais, Gilles, Lear, Scott A, Teo, Koon, Yusuf, Salim
Format: Journal Article
Sprache:Englisch
Veröffentlicht: Waltham, MA Massachusetts Medical Society 14.08.2014
Schlagworte:
Adult
Biological and medical sciences
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Cardiovascular Diseases/epidemiology/etiology
Clinical Medicine
Death
Diet
Dietary/administration & dosage/adverse effects
Epidemiology
Excretion
Family medical history
Female
Follow-Up Studies
General aspects
Health risk assessment
Humans
Klinisk medicin
Linear Models
Male
Medical research
Medical sciences
Middle Aged
Mortality
Potassium
Potassium - administration & dosage
Potassium - urine
Potassium/administration & dosage/urine
Sodium
Sodium - urine
Sodium, Dietary - administration & dosage
Sodium, Dietary - adverse effects
Urine
Ontario Canada
Canada
Turkey
China
India
Medicine
Excretion
Prognosis
Sodium
Mortality
Inorganic element
Potassium
ISSN:0028-4793, 1533-4406, 1533-4406
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In a large study in 17 countries, an estimated sodium intake that was either higher or lower than the average estimated sodium intake was associated with an increased risk of cardiovascular events. A higher-than-average potassium intake was associated with reduced risk. Most of the global population consumes between 3.0 and 6.0 g of sodium per day (7.5 to 15.0 g of salt per day). 1 , 2 Guidelines on cardiovascular disease prevention recommend a maximum sodium intake of 1.5 to 2.4 g per day, but achieving this target will require a substantial change in diet for most people. 3 – 5 Although clinical trials have shown a reduction in blood pressure with a reduced sodium intake, to our knowledge, no large randomized trial has been conducted to document reductions in the risk of cardiovascular disease with low sodium intake. 6 Prospective cohort studies have shown inconsistent . . .
Bibliographie:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
content type line 23
ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa1311889