Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures

Systems approaches have been used to describe molecular signatures driving immunity to influenza vaccination in humans. Whether such signatures are similar across multiple seasons and in diverse populations is unknown. We applied systems approaches to study immune responses in young, elderly, and di...

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Bibliographic Details

Published in:	Immunity (Cambridge, Mass.) Vol. 43; no. 6; pp. 1186 - 1198
Main Authors:	Nakaya, Helder I, Hagan, Thomas, Duraisingham, Sai S, Lee, Eva K, Kwissa, Marcin, Rouphael, Nadine, Frasca, Daniela, Gersten, Merril, Mehta, Aneesh K, Gaujoux, Renaud, Li, Gui-Mei, Gupta, Shakti, Ahmed, Rafi, Mulligan, Mark J, Shen-Orr, Shai, Blomberg, Bonnie B, Subramaniam, Shankar, Pulendran, Bali
Format:	Journal Article
Language:	English
Published:	United States 15.12.2015
Subjects:	Adult Aged Antibodies, Viral - blood Antibodies, Viral - genetics Female Flow Cytometry Humans Influenza Vaccines - immunology Influenza, Human - prevention & control Male Middle Aged Oligonucleotide Array Sequence Analysis Seasons Systems Analysis Transcriptome - immunology
ISSN:	1097-4180
Online Access:	Get more information
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