Using Computational Fluid Dynamics Software to Estimate Circulation Time Distributions in Bioreactors

Nonideal mixing in many fermentation processes can lead to concentration gradients in nutrients, oxygen, and pH, among others. These gradients are likely to influence cellular behavior, growth, or yield of the fermentation process. Frequency of exposure to these gradients can be defined by the circu...

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Bibliographic Details
Published in:Biotechnology progress Vol. 19; no. 5; pp. 1480 - 1486
Main Authors: Davidson, Kyle M., Sushil, Shrinivasan, Eggleton, Charles D., Marten, Mark R.
Format: Journal Article
Language:English
Published: USA American Chemical Society 2003
American Institute of Chemical Engineers
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ISSN:8756-7938, 1520-6033
Online Access:Get full text
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