Choroidal and retinal thinning in chronic kidney disease independently associate with eGFR decline and are modifiable with treatment

In patients with chronic kidney disease (CKD), there is an unmet need for novel biomarkers that reliably track kidney injury, demonstrate treatment-response, and predict outcomes. Here, we investigate the potential of retinal optical coherence tomography (OCT) to achieve these ends in a series of pr...

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Bibliographic Details
Published in:	Nature communications Vol. 14; no. 1; pp. 7720 - 13
Main Authors:	Farrah, Tariq E., Pugh, Dan, Chapman, Fiona A., Godden, Emily, Balmforth, Craig, Oniscu, Gabriel C., Webb, David J., Dhillon, Baljean, Dear, James W., Bailey, Matthew A., Gallacher, Peter J., Dhaun, Neeraj
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 05.12.2023 Nature Publishing Group Nature Portfolio
Subjects:	631/443/592/75/593/2724 692/4022/1585/104/1586 692/53/2422 Biomarkers Choroid - diagnostic imaging Dialysis Epidermal growth factor receptors Humanities and Social Sciences Humans Injuries Kidney diseases Kidney transplantation Kidney transplants multidisciplinary Optical Coherence Tomography Organ donors Prospective Studies Renal failure Renal Insufficiency, Chronic Retina Retina - diagnostic imaging Retinal Degeneration Science Science (multidisciplinary) Thickness Thinning Tomography, Optical Coherence - methods
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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