The Key Roles of Interferon Lambda in Human Molecular Defense against Respiratory Viral Infections

Interferons (IFN) are crucial for the innate immune response. Slightly more than two decades ago, a new type of IFN was discovered: the lambda IFN (type III IFN). Like other IFN, the type III IFN display antiviral activity against a wide variety of infections, they induce expression of antiviral, in...

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Vydáno v:	Pathogens (Basel) Ročník 9; číslo 12; s. 989
Hlavní autoři:	Lozhkov, Alexey A., Klotchenko, Sergey A., Ramsay, Edward S., Moshkoff, Herman D., Moshkoff, Dmitry A., Vasin, Andrey V., Salvato, Maria S.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Switzerland MDPI AG 26.11.2020 MDPI
Témata:	Adaptive immunity Antiviral activity Antiviral agents antiviral properties Bacterial diseases bacterial infections Epithelial cells epithelium Gene expression genes humans Immune response Immune system infection Influenza Innate immunity Interferon interferon stimulated genes interferons interferons-α/β interferons-λ Kinases Mucosa Myxovirus resistance proteins nose Orthomyxoviridae pandemic Pandemics Pathogenesis pathogens Public health receptors respiratory viruses Review risk Sensors shape therapeutics Viral infections Viruses influenza innate immunity interferons-α/β respiratory viruses interferon stimulated genes interferons-λ
ISSN:	2076-0817, 2076-0817
On-line přístup:	Získat plný text
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