The effect of casein and calcium containing paste on plaque pH following a subsequent carbohydrate challenge

Previous research has shown that regular use of CPP–ACP increases calcium and inorganic phosphates in plaque and reduces enamel mineral loss. The aim of this study was to investigate if a CPP–ACP-containing paste would neutralize acidic challenges in dental plaque following sucrose rinse. Plaque pH...

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Vydáno v:	Journal of dentistry Ročník 37; číslo 7; s. 522 - 526
Hlavní autoři:	Caruana, Paul Chetcuti, Mulaify, Sami Al, Moazzez, Rebecca, Bartlett, David
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	England Elsevier Ltd 01.07.2009 Elsevier Limited
Témata:	Adult Buffers Cariogenic Agents - adverse effects Cariostatic Agents - therapeutic use Caseins - therapeutic use CPP–ACP Cross-Over Studies Dental Plaque - physiopathology Dentistry Double-Blind Method Female Humans Hydrogen-Ion Concentration Ion-Selective Electrodes Male Measurement Plaque pH Sorbitol - adverse effects Sucrose Sucrose - adverse effects Sweetening Agents - adverse effects Time Factors Toothpastes - therapeutic use Measurement pH Sucrose Plaque pH CPP–ACP
ISSN:	0300-5712, 1879-176X
On-line přístup:	Získat plný text
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Shrnutí:	Previous research has shown that regular use of CPP–ACP increases calcium and inorganic phosphates in plaque and reduces enamel mineral loss. The aim of this study was to investigate if a CPP–ACP-containing paste would neutralize acidic challenges in dental plaque following sucrose rinse. Plaque pH was measured on 15 subjects in a cross-over study with and without prior application of the paste and with and without CPP–ACP. On each occasion, subjects rinsed with 10% sucrose and sorbitol solutions for 2 min in randomized order. The results showed the median lowest pH without paste was 4.8 (IQR: 4.7–5.0) and with mousse 5.6 (IQR: 5.5–5.6 and p < 0.001). The median lowest pH was 5.0 (IQR: 4.9–5.3) without CPP–ACP and with CPP–ACP was 5.8 (5.6–6.1 and p < 0.001). The time that pH remained below 5.7 and the time to return to resting pH showed similar differences in all subjects ( p < 0.01). The results indicate that prior application of a CPP–ACP-containing paste reduced the fall in plaque pH following a sucrose challenge.
Bibliografie:	ObjectType-Article-2 SourceType-Scholarly Journals-1 content type line 14 ObjectType-Undefined-1 ObjectType-Feature-3 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-3
ISSN:	0300-5712 1879-176X
DOI:	10.1016/j.jdent.2009.03.010