Circulating microRNAs as biomarkers in patients with allergic rhinitis and asthma

MicroRNAs (miRNAs) are emerging as important regulatory molecules that might be involved in the pathogenesis of various diseases. Circulating miRNAs might be noninvasive biomarkers to diagnose and characterize asthma and allergic rhinitis (AR). We sought to determine whether miRNAs are differentiall...

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Vydáno v:	Journal of allergy and clinical immunology Ročník 137; číslo 5; s. 1423 - 1432
Hlavní autoři:	Panganiban, Ronaldo P., Wang, Yanli, Howrylak, Judie, Chinchilli, Vernon M., Craig, Timothy J., August, Avery, Ishmael, Faoud T.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Elsevier Inc 01.05.2016 Elsevier Limited
Témata:	Adult allergic rhinitis Allergy and Immunology Asthma Asthma - blood Asthma - genetics biomarker Biomarkers Biomarkers - blood Cluster analysis Disease Female Gene expression Humans inflammation Laboratories Male microRNA MicroRNAs MicroRNAs - blood Middle Aged Pathogenesis Plasma posttranscriptional regulation Rhinitis, Allergic - blood Rhinitis, Allergic - genetics biomarker MAPK Asthma PCA posttranscriptional regulation AR Ct NF-κB inflammation microRNA KEGG miRNA qPCR allergic rhinitis plasma Kyoto Encyclopedia of Genes and Genomes Mitogen-activated protein kinase Real-time quantitative PCR Cycle threshold Nuclear factor κB Principal component analysis
ISSN:	0091-6749, 1097-6825
On-line přístup:	Získat plný text
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