Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association

Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, particularly among young women and individuals with few conventional atherosclerotic risk factors. Patient-initiated research has spurred increased awa...

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Vydáno v:	Circulation (New York, N.Y.) Ročník 137; číslo 19; s. e523
Hlavní autoři:	Hayes, Sharonne N, Kim, Esther S H, Saw, Jacqueline, Adlam, David, Arslanian-Engoren, Cynthia, Economy, Katherine E, Ganesh, Santhi K, Gulati, Rajiv, Lindsay, Mark E, Mieres, Jennifer H, Naderi, Sahar, Shah, Svati, Thaler, David E, Tweet, Marysia S, Wood, Malissa J
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 08.05.2018
Témata:	American Heart Association Cardiac Imaging Techniques - standards Cardiovascular Agents - therapeutic use Consensus Conservative Treatment - standards Coronary Artery Bypass - standards Coronary Vessel Anomalies - diagnostic imaging Coronary Vessel Anomalies - mortality Coronary Vessel Anomalies - therapy Female Humans Male Middle Aged Percutaneous Coronary Intervention - standards Predictive Value of Tests Pregnancy Prevalence Risk Assessment Risk Factors Treatment Outcome United States Vascular Diseases - congenital Vascular Diseases - diagnostic imaging Vascular Diseases - mortality Vascular Diseases - therapy United States coronary artery dissection, spontaneous fibromuscular dysplasia myocardial infarction AHA Scientific Statements women
ISSN:	1524-4539, 1524-4539
On-line přístup:	Zjistit podrobnosti o přístupu
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Abstract	Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, particularly among young women and individuals with few conventional atherosclerotic risk factors. Patient-initiated research has spurred increased awareness of SCAD, and improved diagnostic capabilities and findings from large case series have led to changes in approaches to initial and long-term management and increasing evidence that SCAD not only is more common than previously believed but also must be evaluated and treated differently from atherosclerotic myocardial infarction. High rates of recurrent SCAD; its association with female sex, pregnancy, and physical and emotional stress triggers; and concurrent systemic arteriopathies, particularly fibromuscular dysplasia, highlight the differences in clinical characteristics of SCAD compared with atherosclerotic disease. Recent insights into the causes of, clinical course of, treatment options for, outcomes of, and associated conditions of SCAD and the many persistent knowledge gaps are presented.
AbstractList	Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, particularly among young women and individuals with few conventional atherosclerotic risk factors. Patient-initiated research has spurred increased awareness of SCAD, and improved diagnostic capabilities and findings from large case series have led to changes in approaches to initial and long-term management and increasing evidence that SCAD not only is more common than previously believed but also must be evaluated and treated differently from atherosclerotic myocardial infarction. High rates of recurrent SCAD; its association with female sex, pregnancy, and physical and emotional stress triggers; and concurrent systemic arteriopathies, particularly fibromuscular dysplasia, highlight the differences in clinical characteristics of SCAD compared with atherosclerotic disease. Recent insights into the causes of, clinical course of, treatment options for, outcomes of, and associated conditions of SCAD and the many persistent knowledge gaps are presented. Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, particularly among young women and individuals with few conventional atherosclerotic risk factors. Patient-initiated research has spurred increased awareness of SCAD, and improved diagnostic capabilities and findings from large case series have led to changes in approaches to initial and long-term management and increasing evidence that SCAD not only is more common than previously believed but also must be evaluated and treated differently from atherosclerotic myocardial infarction. High rates of recurrent SCAD; its association with female sex, pregnancy, and physical and emotional stress triggers; and concurrent systemic arteriopathies, particularly fibromuscular dysplasia, highlight the differences in clinical characteristics of SCAD compared with atherosclerotic disease. Recent insights into the causes of, clinical course of, treatment options for, outcomes of, and associated conditions of SCAD and the many persistent knowledge gaps are presented.Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death, particularly among young women and individuals with few conventional atherosclerotic risk factors. Patient-initiated research has spurred increased awareness of SCAD, and improved diagnostic capabilities and findings from large case series have led to changes in approaches to initial and long-term management and increasing evidence that SCAD not only is more common than previously believed but also must be evaluated and treated differently from atherosclerotic myocardial infarction. High rates of recurrent SCAD; its association with female sex, pregnancy, and physical and emotional stress triggers; and concurrent systemic arteriopathies, particularly fibromuscular dysplasia, highlight the differences in clinical characteristics of SCAD compared with atherosclerotic disease. Recent insights into the causes of, clinical course of, treatment options for, outcomes of, and associated conditions of SCAD and the many persistent knowledge gaps are presented.
Author	Naderi, Sahar Ganesh, Santhi K Tweet, Marysia S Gulati, Rajiv Hayes, Sharonne N Mieres, Jennifer H Wood, Malissa J Arslanian-Engoren, Cynthia Economy, Katherine E Shah, Svati Kim, Esther S H Thaler, David E Saw, Jacqueline Adlam, David Lindsay, Mark E
Author_xml	– sequence: 1 givenname: Sharonne N surname: Hayes fullname: Hayes, Sharonne N – sequence: 2 givenname: Esther S H surname: Kim fullname: Kim, Esther S H – sequence: 3 givenname: Jacqueline surname: Saw fullname: Saw, Jacqueline – sequence: 4 givenname: David surname: Adlam fullname: Adlam, David – sequence: 5 givenname: Cynthia surname: Arslanian-Engoren fullname: Arslanian-Engoren, Cynthia – sequence: 6 givenname: Katherine E surname: Economy fullname: Economy, Katherine E – sequence: 7 givenname: Santhi K surname: Ganesh fullname: Ganesh, Santhi K – sequence: 8 givenname: Rajiv surname: Gulati fullname: Gulati, Rajiv – sequence: 9 givenname: Mark E surname: Lindsay fullname: Lindsay, Mark E – sequence: 10 givenname: Jennifer H surname: Mieres fullname: Mieres, Jennifer H – sequence: 11 givenname: Sahar surname: Naderi fullname: Naderi, Sahar – sequence: 12 givenname: Svati surname: Shah fullname: Shah, Svati – sequence: 13 givenname: David E surname: Thaler fullname: Thaler, David E – sequence: 14 givenname: Marysia S surname: Tweet fullname: Tweet, Marysia S – sequence: 15 givenname: Malissa J surname: Wood fullname: Wood, Malissa J
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/29472380$$D View this record in MEDLINE/PubMed
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References	30370106 - J Thorac Dis. 2018 Sep;10(Suppl 26):S3169-S3175. doi: 10.21037/jtd.2018.07.136.
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Snippet	Spontaneous coronary artery dissection (SCAD) has emerged as an important cause of acute coronary syndrome, myocardial infarction, and sudden death,...
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SubjectTerms	American Heart Association Cardiac Imaging Techniques - standards Cardiovascular Agents - therapeutic use Consensus Conservative Treatment - standards Coronary Artery Bypass - standards Coronary Vessel Anomalies - diagnostic imaging Coronary Vessel Anomalies - mortality Coronary Vessel Anomalies - therapy Female Humans Male Middle Aged Percutaneous Coronary Intervention - standards Predictive Value of Tests Pregnancy Prevalence Risk Assessment Risk Factors Treatment Outcome United States Vascular Diseases - congenital Vascular Diseases - diagnostic imaging Vascular Diseases - mortality Vascular Diseases - therapy
Title	Spontaneous Coronary Artery Dissection: Current State of the Science: A Scientific Statement From the American Heart Association
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