Thrombomodulin: a multifunctional receptor modulating the endothelial quiescence

Thrombomodulin (TM) is a type 1 receptor best known for its function as an anticoagulant cofactor for thrombin activation of protein C on the surface of vascular endothelial cells. In addition to its anticoagulant cofactor function, TM also regulates fibrinolysis, complement, and inflammatory pathwa...

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Bibliographic Details
Published in:	Journal of thrombosis and haemostasis Vol. 22; no. 4; pp. 905 - 914
Main Authors:	Giri, Hemant, Biswas, Indranil, Rezaie, Alireza R.
Format:	Journal Article
Language:	English
Published:	England Elsevier Inc 01.04.2024
Subjects:	Anticoagulants coagulation Endothelial Cells - metabolism Humans inflammation Phosphoric Monoester Hydrolases Protein C - metabolism signal transduction Tensins thrombin Thrombin - metabolism thrombomodulin Thrombomodulin - metabolism thrombin inflammation signal transduction coagulation thrombomodulin
ISSN:	1538-7836, 1538-7933, 1538-7836
Online Access:	Get full text
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