Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer

Local cryoablation can engender systemic immune activation/anticancer responses in tumors otherwise resistant to immune checkpoint blockade (ICB). We evaluated the safety/tolerability of preoperative cryoablation plus ipilimumab and nivolumab in 5 early-stage/resectable breast cancers. The primary e...

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Bibliographic Details
Published in:iScience Vol. 27; no. 2; p. 108880
Main Authors: Comen, Elizabeth, Budhu, Sadna, Elhanati, Yuval, Page, David, Rasalan-Ho, Teresa, Ritter, Erika, Wong, Phillip, Plitas, George, Patil, Sujata, Brogi, Edi, Jochelson, Maxine, Bryce, Yolanda, Solomon, Stephen B., Norton, Larry, Merghoub, Taha, McArthur, Heather L.
Format: Journal Article
Language:English
Published: United States Elsevier Inc 16.02.2024
Elsevier
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ISSN:2589-0042, 2589-0042
Online Access:Get full text
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