Identifying and removing haplotypic duplication in primary genome assemblies

Abstract Motivation Rapid development in long-read sequencing and scaffolding technologies is accelerating the production of reference-quality assemblies for large eukaryotic genomes. However, haplotype divergence in regions of high heterozygosity often results in assemblers creating two copies rath...

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Bibliographic Details

Published in:	Bioinformatics Vol. 36; no. 9; pp. 2896 - 2898
Main Authors:	Guan, Dengfeng, McCarthy, Shane A, Wood, Jonathan, Howe, Kerstin, Wang, Yadong, Durbin, Richard
Format:	Journal Article
Language:	English
Published:	England Oxford University Press 01.05.2020
Subjects:	Applications Notes Genome Haplotypes High-Throughput Nucleotide Sequencing Sequence Analysis, DNA Software
ISSN:	1367-4803, 1367-4811, 1460-2059, 1367-4811
Online Access:	Get full text
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