Antibacterial, anticancer and antioxidant potential of silver nanoparticles engineered using Trigonella foenum-graecum seed extract

In this study, the authors report a simple and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) using Trigonella foenum-graecum (TFG) seed extract. They explored several parameters dictating the biosynthesis of TFG-AgNPs such as reaction time, temperature, concentration of AgNO3...

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Bibliographic Details
Published in:IET nanobiotechnology Vol. 12; no. 4; pp. 526 - 533
Main Authors: Goyal, Shivangi, Gupta, Nidhi, Kumar, Ajeet, Chatterjee, Sreemoyee, Nimesh, Surendra
Format: Journal Article
Language:English
Published: United States The Institution of Engineering and Technology 01.06.2018
Subjects:
AgNO3 concentration
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
antibacterial activity
antibacterial potential
anticancer potential
Antineoplastic Agents - chemistry
Antineoplastic Agents - pharmacology
antioxidant potential
Antioxidants - chemistry
Antioxidants - pharmacology
biochemistry
biomedical materials
biosynthesis
Biphenyl Compounds
cancer
Cell Line, Tumor
Cell Survival
cellular biophysics
dynamic light scattering
eco‐friendly method
energy dispersive X‐ray spectroscopy
Escherichia coli
field emission electron microscopy
Fourier transform infrared spectra
Fourier transform infrared spectroscopy
Green Chemistry Technology
Humans
light scattering
Metal Nanoparticles - chemistry
microorganisms
nanofabrication
nanomedicine
nanoparticles
Particle Size
physicochemical characterisation
Picrates
Plant Extracts - chemistry
Plant Extracts - metabolism
Plant Extracts - pharmacology
Proteus vulgaris
Pseudomonas aeruginosa
reaction time
Research Article
Seeds - chemistry
Seeds - metabolism
silver
Silver - chemistry
Silver - pharmacology
silver nanoparticles
size determination
skin
skin cancer cell line A431
Spectroscopy, Fourier Transform Infrared
Staphylococcus aureus
TFG extract amount
TFG‐AgNPs size
Trigonella - chemistry
Trigonella foenum‐graecum seed extract
X‐ray chemical analysis
X‐ray diffraction
antibacterial activity
antioxidant potential
particle size
cellular biophysics
physicochemical characterisation
Fourier transform infrared spectra
Escherichia coli
Ag
nanofabrication
skin
X-ray diffraction
light scattering
TFG-AgNPs size
TFG extract amount
anticancer potential
nanoparticles
energy dispersive X-ray spectroscopy
biosynthesis
Pseudomonas aeruginosa
Staphylococcus aureus
dynamic light scattering
size determination
nanomedicine
AgNO3 concentration
Trigonella foenum-graecum seed extract
skin cancer cell line A431
silver nanoparticles
microorganisms
field emission electron microscopy
biomedical materials
biochemistry
X-ray chemical analysis
antibacterial potential
reaction time
cancer
silver
Fourier transform infrared spectroscopy
eco-friendly method
Proteus vulgaris
ISSN:1751-8741, 1751-875X, 1751-875X
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Summary:In this study, the authors report a simple and eco-friendly method for the synthesis of silver nanoparticles (AgNPs) using Trigonella foenum-graecum (TFG) seed extract. They explored several parameters dictating the biosynthesis of TFG-AgNPs such as reaction time, temperature, concentration of AgNO3, and TFG extract amount. Physicochemical characterisation of TFG-AgNPs was done on dynamic light scattering (DLS), field emission electron microscopy, energy dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy. The size determination studies using DLS revealed of TFG-AgNPs size between 95 and 110 nm. The antibacterial activity was studied against Escherichia coli, Proteus vulgaris, Pseudomonas aeruginosa and Staphylococcus aureus. The biosynthesised TFG-AgNPs showed remarkable anticancer efficacy against skin cancer cell line, A431 and also exhibited significant antioxidant efficacy.
Bibliography:Both the authors contributed equally.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1751-8741
1751-875X
1751-875X
DOI:10.1049/iet-nbt.2017.0089