Extracellular matrix in the trabecular meshwork: Intraocular pressure regulation and dysregulation in glaucoma

The trabecular meshwork (TM) is located in the anterior segment of the eye and is responsible for regulating the outflow of aqueous humor. Increased resistance to aqueous outflow causes intraocular pressure to increase, which is the primary risk factor for glaucoma. TM cells reside on a series of fe...

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Bibliographic Details
Published in:	Experimental eye research Vol. 133; pp. 112 - 125
Main Authors:	Vranka, Janice A., Kelley, Mary J., Acott, Ted S., Keller, Kate E.
Format:	Journal Article
Language:	English
Published:	England Elsevier Ltd 01.04.2015
Subjects:	animal models Animals Aqueous Humor - physiology extracellular matrix Extracellular Matrix - physiology gene mutations glaucoma Glaucoma - metabolism Glaucoma - physiopathology Humans intraocular pressure Intraocular Pressure - physiology perfusion culture trabecular meshwork Trabecular Meshwork - physiology animal models intraocular pressure perfusion culture glaucoma gene mutations extracellular matrix trabecular meshwork
ISSN:	0014-4835, 1096-0007, 1096-0007
Online Access:	Get full text
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