Primary results of the randomized trial of metformin administration in polycystic kidney disease (TAME PKD)

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by growth of kidney cysts and glomerular filtration rate (GFR) decline. Metformin was found to impact cystogenesis in preclinical models of polycystic disease, is generally considered safe and may be a promising candidate for clin...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Kidney international Jg. 100; H. 3; S. 684
Hauptverfasser:	Perrone, Ronald D, Abebe, Kaleab Z, Watnick, Terry J, Althouse, Andrew D, Hallows, Kenneth R, Lalama, Christina M, Miskulin, Dana C, Seliger, Stephen L, Tao, Cheng, Harris, Peter C, Bae, Kyongtae Ty
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 01.09.2021
Schlagworte:	Adult Cysts Disease Progression Glomerular Filtration Rate Humans Kidney Metformin - adverse effects Polycystic Kidney, Autosomal Dominant - drug therapy clinical trial total kidney volume metformin autosomal dominant polycystic kidney disease estimated glomerular filtration rate
ISSN:	1523-1755, 1523-1755
Online-Zugang:	Weitere Angaben
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!