Primary results of the randomized trial of metformin administration in polycystic kidney disease (TAME PKD)

Autosomal dominant polycystic kidney disease (ADPKD) is characterized by growth of kidney cysts and glomerular filtration rate (GFR) decline. Metformin was found to impact cystogenesis in preclinical models of polycystic disease, is generally considered safe and may be a promising candidate for clin...

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Vydáno v:	Kidney international Ročník 100; číslo 3; s. 684
Hlavní autoři:	Perrone, Ronald D, Abebe, Kaleab Z, Watnick, Terry J, Althouse, Andrew D, Hallows, Kenneth R, Lalama, Christina M, Miskulin, Dana C, Seliger, Stephen L, Tao, Cheng, Harris, Peter C, Bae, Kyongtae Ty
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.09.2021
Témata:	Adult Cysts Disease Progression Glomerular Filtration Rate Humans Kidney Metformin - adverse effects Polycystic Kidney, Autosomal Dominant - drug therapy clinical trial total kidney volume metformin autosomal dominant polycystic kidney disease estimated glomerular filtration rate
ISSN:	1523-1755, 1523-1755
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