Exosomal mitochondrial tRNAs and miRNAs as potential predictors of inflammation in renal proximal tubular epithelial cells

Exosomes have emerged as a valuable repository of novel biomarkers for human diseases such as chronic kidney disease (CKD). From a healthy control group, we performed microRNA (miRNA) profiling of urinary exosomes and compared it with a cell culture model of renal proximal tubular epithelial cells (...

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Bibliographic Details
Published in:	Molecular therapy. Nucleic acids Vol. 28; pp. 794 - 813
Main Authors:	Ranches, Glory, Zeidler, Maximilian, Kessler, Roman, Hoelzl, Martina, Hess, Michael W., Vosper, Jonathan, Perco, Paul, Schramek, Herbert, Kummer, Kai K., Kress, Michaela, Krogsdam, Anne, Rudnicki, Michael, Mayer, Gert, Huettenhofer, Alexander
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 14.06.2022 American Society of Gene & Cell Therapy Elsevier
Subjects:	biomarkers chronic kidney disease cytokines exosomes inflammation and fibrosis miRNAs MT: Oligonucleotides: Diagnostics and Biosensors mtRNAs ncRNAs Original renal proximal tubular epithelial cells chronic kidney disease miRNAs MT: Oligonucleotides: Diagnostics and Biosensors renal proximal tubular epithelial cells exosomes biomarkers inflammation and fibrosis cytokines mtRNAs ncRNAs
ISSN:	2162-2531, 2162-2531
Online Access:	Get full text
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