Challenging the utility of polygenic scores for social science: Environmental confounding, downward causation, and unknown biology

The sociogenomics revolution is upon us, we are told. Whether revolutionary or not, sociogenomics is poised to flourish given the ease of incorporating polygenic scores (or PGSs) as “genetic propensities” for complex traits into social science research. Pointing to evidence of ubiquitous heritabilit...

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Bibliographic Details
Published in:	The Behavioral and brain sciences Vol. 46; p. e207
Main Author:	Burt, Callie H.
Format:	Journal Article
Language:	English
Published:	New York, USA Cambridge University Press 01.01.2023
Subjects:	A. R Anopheles Behavior Behavior genetics Biology Charney, Evan Datasets Educational attainment Environmental effects Ethics Genes Genetic aspects Genetics Genomes Harrison, S Heritability Humans Multifactorial Inheritance - genetics Polygenic inheritance Science Scientists Social research Social science research Social Sciences Sociopolitical factors Target Article New York Netherlands United States United Kingdom California Australia Germany GWAS polygenic scores population stratification statistical genetics sociogenomics human potential gene–environment correlation behavior genetics environmental confounding genetic heterogeneity
ISSN:	0140-525X, 1469-1825, 1469-1825
Online Access:	Get full text
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