FGF21 Signals to Glutamatergic Neurons in the Ventromedial Hypothalamus to Suppress Carbohydrate Intake

Fibroblast growth factor 21 (FGF21) is an endocrine hormone produced by the liver that regulates nutrient and metabolic homeostasis. FGF21 production is increased in response to macronutrient imbalance and signals to the brain to suppress sugar intake and sweet-taste preference. However, the central...

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Bibliographic Details

Published in:	Cell metabolism Vol. 32; no. 2; p. 273
Main Authors:	Jensen-Cody, Sharon O, Flippo, Kyle H, Claflin, Kristin E, Yavuz, Yavuz, Sapouckey, Sarah A, Walters, Grant C, Usachev, Yuriy M, Atasoy, Deniz, Gillum, Matthew P, Potthoff, Matthew J
Format:	Journal Article
Language:	English
Published:	United States 04.08.2020
Subjects:	VMH liver hepatokine PVN sugar intake sweet-taste preference brain macronutrient glucose sensing hypothalamus FGF21
ISSN:	1932-7420, 1932-7420
Online Access:	Get more information
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