IL-6-mediated hepatocyte production is the primary source of plasma and urine neutrophil gelatinase-associated lipocalin during acute kidney injury

Neutrophil gelatinase associated lipocalin (NGAL, Lcn2) is the most widely studied biomarker of acute kidney injury (AKI). Previous studies have demonstrated that NGAL is produced by the kidney and released into the urine and plasma. Consequently, NGAL is currently considered a tubule specific injur...

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Bibliographic Details

Published in:	Kidney international Vol. 97; no. 5; p. 966
Main Authors:	Skrypnyk, Nataliya I, Gist, Katja M, Okamura, Kayo, Montford, John R, You, Zhiying, Yang, Haichun, Moldovan, Radu, Bodoni, Evelyn, Blaine, Judith T, Edelstein, Charles L, Soranno, Danielle E, Kirkbride-Romeo, Lara A, Griffin, Benjamin R, Altmann, Chris, Faubel, Sarah
Format:	Journal Article
Language:	English
Published:	United States 01.05.2020
Subjects:	ischemia reperfusion acute kidney injury cytokines nephrotoxicity biomarkers IL-6
ISSN:	1523-1755, 1523-1755
Online Access:	Get more information
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