IL-6-mediated hepatocyte production is the primary source of plasma and urine neutrophil gelatinase-associated lipocalin during acute kidney injury

Neutrophil gelatinase associated lipocalin (NGAL, Lcn2) is the most widely studied biomarker of acute kidney injury (AKI). Previous studies have demonstrated that NGAL is produced by the kidney and released into the urine and plasma. Consequently, NGAL is currently considered a tubule specific injur...

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Vydáno v:	Kidney international Ročník 97; číslo 5; s. 966
Hlavní autoři:	Skrypnyk, Nataliya I, Gist, Katja M, Okamura, Kayo, Montford, John R, You, Zhiying, Yang, Haichun, Moldovan, Radu, Bodoni, Evelyn, Blaine, Judith T, Edelstein, Charles L, Soranno, Danielle E, Kirkbride-Romeo, Lara A, Griffin, Benjamin R, Altmann, Chris, Faubel, Sarah
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.05.2020
Témata:	ischemia reperfusion acute kidney injury cytokines nephrotoxicity biomarkers IL-6
ISSN:	1523-1755, 1523-1755
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